The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia - ScienceDirect
Deubiquitinase USP13 dictates MCL1 stability and sensitivity to BH3 mimetic inhibitors | Nature Communications
Frontiers | Novel MDM2 Inhibitor XR-2 Exerts Potent Anti-Tumor Efficacy and Overcomes Enzalutamide Resistance in Prostate Cancer
JAK/BCL2 inhibition acts synergistically with LSD1 inhibitors to selectively target ETP-ALL | Leukemia
Nrf2 overexpression increases the resistance of acute myeloid leukemia to cytarabine by inhibiting replication factor C4 | Cancer Gene Therapy
Cancers | Free Full-Text | Efficacy and Synergy of Small Molecule Inhibitors Targeting FLT3-ITD+ Acute Myeloid Leukemia | HTML
Temsirolimus Activates Autophagy and Ameliorates Cardiomyopathy Caused by Lamin A/C Gene Mutation | Science Translational Medicine
Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy | Cell Death & Differentiation
RSPO2 inhibits BMP signaling to promote self-renewal in acute myeloid leukemia - ScienceDirect
IJMS | Free Full-Text | Proteasome Inhibitors Interrupt the Activation of Non-Canonical NF-κB Signaling Pathway and Induce Cell Apoptosis in Cytarabine-Resistant HL60 Cells | HTML
Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms | Leukemia
Targeted activation of GPER enhances the efficacy of venetoclax by boosting leukemic pyroptosis and CD8+ T cell immune function in acute myeloid leukemia | Cell Death & Disease
Interplay between protein acetylation and ubiquitination controls MCL1 protein stability - ScienceDirect
Cancers | Free Full-Text | Critical Requirement of SOS1 for Development of BCR/ABL-Driven Chronic Myelogenous Leukemia | HTML
Induced differentiation of acute myeloid leukemia cells by activation of retinoid X and liver X receptors | Leukemia
Metabolic perturbations sensitize triple-negative breast cancers to apoptosis induced by BH3 mimetics | Science Signaling
CD123 Antagonistic Peptides Assembled with Nanomicelles Act as Monotherapeutics to Combat Refractory Acute Myeloid Leukemia | ACS Applied Materials & Interfaces
Hymeglusin Enhances the Pro-Apoptotic Effects of Venetoclax in Acute Myeloid Leukemia - Frontiers
c-Myc plays a critical role in the antileukemic activity of the Mcl-1-selective inhibitor AZD5991 in acute myeloid leukemia | SpringerLink
Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells | Journal of Medicinal Chemistry
Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy | Nature Communications
Molecular methods for measurable residual disease in acute myeloid leukemia: where are we and where are we going? | SpringerLink
