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Pan-Assay Interference Compounds (PAINs). | Download Scientific Diagram
Pan-Assay Interference Compounds (PAINs). | Download Scientific Diagram

KNIME Workflow to Assess PAINS Filters in SMARTS Format. Comparison of  RDKit and Indigo Cheminformatics Libraries
KNIME Workflow to Assess PAINS Filters in SMARTS Format. Comparison of RDKit and Indigo Cheminformatics Libraries

FAFDrugs4 PAINS
FAFDrugs4 PAINS

PAINS Filter Tool
PAINS Filter Tool

Back pain as a sign of inferior vena cava filter complications | Cleveland  Clinic Journal of Medicine
Back pain as a sign of inferior vena cava filter complications | Cleveland Clinic Journal of Medicine

PDF] New Substructure Filters for Removal of Pan Assay Interference  Compounds (PAINS) from Screening Libraries and for Their Exclusion in  Bioassays | Scinapse
PDF] New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Scinapse

Identification of a novel selective inhibitor of mutant isocitrate  dehydrogenase 1 at allosteric site by docking-based virtual screening - RSC  Advances (RSC Publishing) DOI:10.1039/C6RA21617J
Identification of a novel selective inhibitor of mutant isocitrate dehydrogenase 1 at allosteric site by docking-based virtual screening - RSC Advances (RSC Publishing) DOI:10.1039/C6RA21617J

A Whole-Cell Screen for Adjunctive and Direct Antimicrobials Active against  Carbapenem-Resistant Enterobacteriaceae - SLAS Discovery
A Whole-Cell Screen for Adjunctive and Direct Antimicrobials Active against Carbapenem-Resistant Enterobacteriaceae - SLAS Discovery

Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility  and Limitations | ACS Chemical Biology
Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology

A PAINS filter | Macs in Chemistry
A PAINS filter | Macs in Chemistry

Chemistry: Chemical con artists foil drug discovery | Nature
Chemistry: Chemical con artists foil drug discovery | Nature

Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility  and Limitations | ACS Chemical Biology
Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology

The SPAM FILTER Metaphor | Explain Pain by Jo Nijs - YouTube
The SPAM FILTER Metaphor | Explain Pain by Jo Nijs - YouTube

Filtering Chemical Libraries
Filtering Chemical Libraries

New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays |  Journal of Medicinal Chemistry
New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Journal of Medicinal Chemistry

Biology must develop herd immunity against bad-actor molecules | PLOS  Pathogens
Biology must develop herd immunity against bad-actor molecules | PLOS Pathogens

Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility  and Limitations | ACS Chemical Biology
Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology

PDF] New substructure filters for removal of pan assay interference  compounds (PAINS) from screening libraries and for their exclusion in  bioassays. | Semantic Scholar
PDF] New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Semantic Scholar

Gains from no real PAINS: Where 'Fair Trial Strategy' stands in the  development of multi-target ligands - ScienceDirect
Gains from no real PAINS: Where 'Fair Trial Strategy' stands in the development of multi-target ligands - ScienceDirect

Highly Promiscuous Small Molecules from Biological Screening Assays Include  Many Pan-Assay Interference Compounds but Also Candi
Highly Promiscuous Small Molecules from Biological Screening Assays Include Many Pan-Assay Interference Compounds but Also Candi

FAFDrugs4 PAINS
FAFDrugs4 PAINS

PAINS filters now on mobile, with MolPrime+ – Cheminformatics 2.0
PAINS filters now on mobile, with MolPrime+ – Cheminformatics 2.0

Can an IVC Filter Cause Pain? • Drugwatcher.org
Can an IVC Filter Cause Pain? • Drugwatcher.org

IJMS | Free Full-Text | Identification and Evaluation of Inhibitors of  Lipase from Malassezia restricta using Virtual High-Throughput Screening  and Molecular Dynamics Studies | HTML
IJMS | Free Full-Text | Identification and Evaluation of Inhibitors of Lipase from Malassezia restricta using Virtual High-Throughput Screening and Molecular Dynamics Studies | HTML

Could an over-reliance on computational PAINS filters prove a costly  mistake for drug discovery?
Could an over-reliance on computational PAINS filters prove a costly mistake for drug discovery?

KNIME Workflow to Assess PAINS Filters in SMARTS Format. Comparison of  RDKit and Indigo Cheminformatics Libraries - Saubern - 2011 - Molecular  Informatics - Wiley Online Library
KNIME Workflow to Assess PAINS Filters in SMARTS Format. Comparison of RDKit and Indigo Cheminformatics Libraries - Saubern - 2011 - Molecular Informatics - Wiley Online Library